Three Approaches to Post-Viral Fatigue

Post-Viral Fatigue & Other Symptoms: Three New Approaches

Wendy Finkelstein, PA-C and I attended an enlightening conference this weekend where we gained valuable insights into Post-Viral Fatigue (PVF). This condition, which often persists after a viral infection (not just covid), can have a profound impact on daily life. However, there is encouraging news. Research has identified three promising strategies for managing PVF: Lithium Orotate, Specialized Pro-resolving Mediators (SPMs), and Plasmalogens. Each of these approaches offers a unique angle for addressing the lingering effects of post-viral infections, providing new hope for those affected.

Lithium Orotate: A Micro-Nutrient with Macro-Benefits

Lithium Orotate, a naturally occurring mineral, is known for its potential benefits in brain health and mood regulation. Unlike the lithium used in psychiatry, Lithium Orotate is available in lower doses and is considered a dietary supplement. In the context of PVF, it’s believed to support neurological health and cognitive function, which are often compromised following viral infections. Studies suggest that low-dose Lithium Orotate could aid in alleviating some of the symptoms associated with Long Covid (1).

A supplement bottle of Minrex by Xymogen

Lithium Orotate is in Minrex!

In addition to all of the highly absorbable and balanced multi-mineral formula in Xymogen’s Minrex, it includes 250 MCG of Lithium Orotate.*


Specialized Pro-resolving Mediators (SPMs): Turning Off the Inflammation Switch

SPMs are a class of compounds derived from fatty acids, playing a crucial role in resolving inflammation – a key component in post-viral syndromes. In Post-Viral Fatigue, prolonged inflammation can lead to persistent fatigue, muscle aches, and cognitive issues. SPMs, found in certain foods and available as supplements, help switch off the inflammatory response, promoting healing and recovery. Including SPM-rich foods in your diet or considering supplementation might provide a beneficial adjunct to your PVF management plan. (2)

SPM Active

SPM Active is designed to help support the body’s natural capacity to respond to physical challenges and resolve the immune response.*

SPMs have been known to support individuals experiencing:

  • Physical discomfort from everyday activities*
  • Exercise-related discomfort*
    Reduced SPM production linked to excess body fat*

Plasmalogens: The New Frontier in Cellular Health

Plasmalogens are a type of phospholipid vital for cell membrane integrity and function. Research suggests that plasmalogens may play a significant role in neuronal health and cognitive function. In Post-Viral Fatigue, where cellular dysfunction is a concern, boosting plasmalogen levels could support cellular repair and improve energy levels. Dietary sources of plasmalogens include seafood and organ meats, but for those seeking higher doses, specialized supplements are also available.

ProdromeNeuro Plasmalogens

ProdromeNeuro™ contains the plasmalogen building blocks for neurons that make up brain gray matter. Neurons are cells that process and transmit information in the body. These plasmalogens commonly become deficient with age.

Integrating These Approaches into Your Post-Viral Regimen

As with any new treatment or supplement, it’s crucial to approach these options under professional guidance. Each individual’s health status, medical history, and current medications must be considered to ensure safety and effectiveness. We encourage you to book a consultation to discuss how these new approaches can be tailored to your unique health needs.

Your journey to recovery from Post-Viral Fatigue can be challenging, but with these emerging approaches, we have new tools at our disposal to aid in your healing journey. Remember, your health and well-being are our utmost priority, and we’re here to support you every step of the way.


Elizabeth Tringali, PA- & Wendy Finkelstein, PA-C

Wendy Finkelstein, PA-C

Wendy Finkelstein, PA-C

Wendy Finkelstein is a board-certified Physician Assistant who believes that aging is a call for celebration and an opportunity to feel grateful for your body and its incredible ability to transform. Wendy believes that deconstructing the common paradigms of the aging process can fully help us to embrace our youth at any age.
With a focus on mitochondrial repair, Wendy approaches Functional Medicine from the cellular level.

About Tringali Vibrant Health

Founded by Functional Medicine Expert Elizabeth Tringali, PA-C, Tringali Vibrant Health is a Functional Medicine and Integrative Practice that looks for the root causes of your health issues to restore optimal, VIBRANT health.

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